Here's an idea I'm tossing around.
Players race to create pixelated creatures using colored cubes. The creatures designed all challenge the previously winning creature to a duel. Players vote on which of the new creatures wins the battle, (they can't vote for their own) and that creature takes the old one's place as the new champion.
Other rules include: If your creature wins, you get a point, but every one else gets to draw more cubes from the pool to add to their collections.
While creating, you can switch out your cubes with different colored ones in the pool, but you have to maintain the same number of cubes.
Once a player thinks he is done, he shouts DONE and all players must stop and be judged as they are.
First player to X points wins.
Alternately, the game could take on a storytelling form, where people race to create people, creatures, or things to fill in the next part of a story.
Yeah, players definitely will be grabbing more than 1 pixel at a time. Maybe 10.
I like this idea because it ties into tall the pixelated art that's becoming popular now. I can see a player who's good enough creating little zelda or mario creatures.
I was lucky enough to find this on amazon. http://www.amazon.com/Assessment-Services-Inc---Centimeter-030-2071/dp/B...
Which might be useful for all sorts of game designers, actually.
Ideally, I'd like to make the game so that after players make their creatures, they get randomized so that people can't tell who made which. It would make it fairer, but it's hard to do when they aren't cards.